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货号： bs-0788R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-0788R
- 英文名称
- intestinal FABP
- 中文名称
- 肠型脂肪酸结合蛋白抗体
- 别 名
- FABP 2; FABP2; FABPI; Fatty acid binding protein 2 intestinal; Fatty acid binding protein intestinal; Fatty acid-binding protein; I-FABP; IFABP; Intestinal fatty acid binding protein 2; MGC133132; FABPI_HUMAN.
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 心血管 细胞生物 免疫学 生长因子和激素 糖尿病
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 15kDa
- 细胞定位
- 细胞浆 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from IFABP:45-132/132
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Intestinal FABP is an intestinal marker. It is expressed in the small intestine. Expression in the mucosal cells of the ileum extends from the midvillar region to the villus tips. It is thought to play a role in the intracellular transport of long chain fatty acids and their acyl CoA esters and may be involved in triglyceride rich lipoprotein synthesis.
Function:
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Expressed in the small intestine and at much lower levels in the large intestine. Highest expression levels in the jejunum.
Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
SWISS:
P12104
Gene ID:
2169
Database links:Entrez Gene: 2169 Human
Entrez Gene: 14079 Mouse
Entrez Gene: 25598 Rat
Omim: 134640 Human
SwissProt: P12104 Human
SwissProt: P55050 Mouse
SwissProt: P02693 Rat
Unigene: 282265 Human
Unigene: 28398 Mouse
Unigene: 91358 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Fabp2脂肪酸结合蛋白-2,参与脂肪酸代谢、运输、消化，该蛋白的异常增高使人的新陈代谢功能异常，影响人体消耗摄入的糖分，从而导致引发糖尿病的发生。FABP2多态性可能与2型糖尿病合并冠心病的胰岛素抵抗相关联。
- 产品图片
Sample: Intestinal(Mouse) Lysate at 30ug;
Primary: Anti-intestinal FABP (bs-0788R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size: 15 kD
Observed band size: 17 kD
Sample: Raji Cell Lysate at 30ug;
Primary: Anti-intestinal FABP (bs-0788R) at 1:300 dilution;
Secondary: HRP conjugated Goat-Anti-rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution;
Predicted band size: 15 kD
Observed band size: 17 kD
Tissue/cell: human colon carcinoma tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-IFABP Polyclonal Antibody, Unconjugated(bs-0788R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining