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货号： bs-2602R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2602R-AP
- 英文名称
- Anti-IL10RB/AP
- 中文名称
- 碱性磷酸酶（AP）标记的白细胞介素-10受体β抗体
- 别 名
- Cd210; CDw210b; CRF2 4; CRF2-4; CRFB4; Cytokine receptor class II; Cytokine receptor class II CRF2 4; Cytokine receptor class-II member 4; Cytokine receptor family 2 member 4; Cytokine receptor family II member 4; D21S58; D21S66; I10R2_HUMAN; IL-10 receptor subunit beta; IL-10R subunit 2; IL-10R subunit beta; IL-10R2; IL-10RB; IL10R2; IL10RB; Interleukin 10 receptor beta; Interleukin-10 receptor subunit 2; Interleukin-10 receptor subunit beta.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IL-10RB
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Interleukin 10 binds specifically and with high affinity to cell surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. Mouse and human cDNA clones encoding the ligand binding IL10 receptor have been isolated. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.
Subcellular Location:
Membrane; Single-pass type I membrane
Similarity:
Belongs to the type II cytokine receptor family.
Contains 2 fibronectin type-III domains.
Database links:Entrez Gene: 3588Human
Entrez Gene: 16155Mouse
Entrez Gene: 304091Rat
Omim: 123889Human
SwissProt: Q08334Human
SwissProt: Q61190Mouse
Unigene: 654593Human
Unigene: 4154Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.