产品中心
当前位置：首页>产品中心Anti-KMT8
货号： bs-6140R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-6140R
- 英文名称
- KMT8
- 中文名称
- 转录因子GATA3结合蛋白G3B抗体
- 别 名
- GATA 3 binding protein G3B; GATA-3-binding protein G3B; HUMHOXY 1; HUMHOXY1; Lysine N methyltransferase 8; Lysine N-methyltransferase 8; MTB ZF; MTB-ZF; MTE binding protein; MTE-binding protein; PR domain containing 2 with ZNF domain; PR domain containing protein 2; PR domain zinc finger protein 2; PR domain-containing protein 2; PR-domain zinc finger protein 2; PRDM 2; PRDM2; PRDM2_HUMAN; Retinoblastoma protein binding zinc finger protein; Retinoblastoma protein interacting zinc- inger protein; retinoblastoma protein-interacting zinc finger protein; Retinoblastoma protein-interacting zinc-finger protein; RIZ 1; RIZ 2; RIZ; RIZ-LSB; RIZ1; RIZ2; Zinc finger DNA binding protein; Zinc finger protein RIZ.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 免疫学 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 189kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KMT8/Riz1/Riz2:1201-1300/1718
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates Lys-9 of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
Function:
S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates Lys-9 of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene.
Subunit:
Binds to the retinoblastoma protein (RB). Interacts with GATA3.
Subcellular Location:
Nucleus.
Tissue Specificity:
Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3.
Similarity:
Contains 8 C2H2-type zinc fingers.
Contains 1 SET domain.
SWISS:
Q13029
Gene ID:
7799
Database links:Entrez Gene: 7799 Human
Entrez Gene: 110593 Mouse
Entrez Gene: 313678 Rat
Omim: 601196 Human
SwissProt: Q13029 Human
SwissProt: Q63755 Rat
Unigene: 371823 Human
Unigene: 202632 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.