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货号： bs-0743R 基本售价： 380.0 元 规格： 20ul
- 规格：20ul
- 价格：380.00元
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-0743R
- 英文名称
- CTGF
- 中文名称
- 结缔组织生长因子抗体
- 别 名
- CCN 2; CCN-2; CCN2; Connective Tissue Growth Factor; CTGF; Hcs 24; Hcs24; Hypertrophic chondrocyte specific protein 24; Hypertrophic chondrocyte-specific gene product 24; Insulin-like Growth Factor-Binding Protein 8; MGC102839; NOV 2; NOV2; Connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP8; IGFBP-8; connective tissue growth factor precursor; CTGF_HUMAN.
- Specific References (3) | bs-0743R has been referenced in 3 publications.[IF=2.24] Tian, Yanyan, et al. "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." International Journal of Clinical and Experimental Pathology 7.6 (2014): 3028-3037. IHC-P ; Rat.PubMed:25031721[IF=8.46] Ciamporcero, E., et al. "YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage." Oncogene (2015). WB ; Human.PubMed:26119935[IF=1.74] Al-hamilly, Nadia Saeed, et al. "Biological roles of KGF, CTGF and TGF-β in cyclosporine-A-and phenytoin-induced gingival overgrowth: A comparative experimental animal study." Archives of oral biology 66 (2016): 38-43. IHC-P ; Rat.PubMed:26894526
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 心血管 免疫学 生长因子和激素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 36kDa
- 细胞定位
- 细胞外基质 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CTGF:221-349/349
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009].
Function:
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Subunit:
Monomer.
Subcellular Location:
Secreted, extracellular space, extracellular matrix. Secreted.
Tissue Specificity:
Expressed in bone marrow and thymic cells. Also expressed one of two Wilms tumors tested.
Similarity:
Belongs to the CCN family.
Contains 1 CTCK (C-terminal cystine knot-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 TSP type-1 domain.
Contains 1 VWFC domain.
SWISS:
P29279
Gene ID:
1490
Database links:Entrez Gene: 1490 Human
Entrez Gene: 64032 Rat
Omim: 121009 Human
SwissProt: P29279 Human
SwissProt: P29268 Mouse
SwissProt: Q9R1E9 Rat
Unigene: 410037 Human
Unigene: 390287 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
生长因子和激素（ Growth Factor and Hormones）
结缔组织生长因子（CTGF）是调节细胞增生、分化和细胞外基质形成的重要效应分子,可调节机体有关组织、细胞生长并与纤维化发生密切相关的一种因子，因而在肌体的各类创伤修复过程中具有重要的生理学意义。
- 产品图片
Sample: Lung Lysate at 40 ug
Primary: Anti- CTGF (bs-0743R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/10000 dilution
Predicted band size: 36 kD
Observed band size: 36 kD
