PARP (cleaved) Whole Cell Lysate Kit PARP | Human
货号：
K150DED-3 基本售价：
询价 规格：
20 plates
产品信息
概述| 货号 | K150DED-3 |
| 描述 | Poly (ADP-ribose) polymerase (PARP) is a nuclear enzyme activated by DNA damage and was one of the first identified death subsrates for caspase-3 in apoptosis. Active PARP transfers ADP-ribose from NAD+ to nuclear proteins, and this modification has been implicated in many fundamental processes like DNA repair, chromatin stability, cell proliferation, and cell death. PARP becomes inactive following cleavage, however the small cleavage product does retain its DNA-binding capabilities, thereby blocking access to damaged DNA and inhibiting further DNA repair. This kit provides assay-specific components for the quantitative determination of PARP (cleaved) (Asp214) in human whole cell lysates. |
| 反应种属 | Human |
| 应用 | Phosphoproteins,Intracellular Signaling |
性能| 说明书 | Cleaved PARP WCL
|
| 供应商 | MSD |
| 存放说明 | Multi-Component |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |
