货号 | K152QTG-4 |
描述 | Mouse KC (KC/GRO)—also known as CXCL1, GROα, neutrophil-activating protein 3 (NAP-3), and melanoma growth stimulating activity alpha (MGSA-α)—is a 10.2 kDa CXC chemokine. KC/GRO is produced by fibroblasts induced by platelet-derived growth factor and expressed in macrophages and endothelial cells. It produces a biological signal by binding to its receptor, CXCR2. During inflammation, it is involved in neutrophil activation and shows hematopoietic activity. Upon secretion from bone marrow stromal cells through proteolytic cleavage, the N-terminal processed form of KC (5-72) shows highly enhanced hematopoietic activity. This chemokine and its receptor are responsible for neutrophil chemotaxis in epidemic keratoconjunctivits.The Mouse KC/GRO Kit provides assay-specific components for the quantitative determination of endogenous KC/GRO in mouse urine, serum, plasma, and cell culture supernatants. |
反应种属 | Mouse |
应用 | Cytokines & Chemokines,Immunology/Inflammation |
说明书 | Proinflammatory Panel 1 mouse Calibrator Insert Proinflammatory Panel 1 mouse Control Insert Proinflammatory Panel 1 mouse Insert |
供应商 | MSD |
样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
灵敏度 | 0.24 pg/mL |
检测范围 | 0.24–1230 pg/mL |
存放说明 | Multi-Component |
产品用途 | For Research Use Only. Not for use in diagnostic procedures. |