| 货号 | K151RJD-4 |
| 描述 | Human interleukin-12/interleukin 23 p40 (IL-12/IL-23p40)—also known as IL-12B, cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), and NK cell stimulatory factor chain 2 (NKSF2)—is a glycosylated 37.2 kDa protein with five internal disulfide bonds. This cytokine can form heterodimers by binding to the IL-12A subunit or the IL-23 p19 subunit to form IL-12 and IL-23, respectively. It can also dimerize with itself to form the p80 homodimer. It acts as a growth factor for activated T and NK cells and stimulates NK/lymphokine-activated killer cells and IFN-γ production. IL-12/IL-23 p40 binds to IL-12Rβ1 which is part of both IL-12 and IL-23 receptor complexes. It is involved in Mendelian susceptibility to mycobacterial disease (MSMD) and psoriasis type 11. The Human IL-12/IL-23p40 Kit provides assay-specific components for the quantitative determination of endogenous IL-12/IL-23p40 in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Cytokine Panel 1 human Calibrator Insert Cytokine Panel 1 human Control Insert Cytokine Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.39 pg/mL |
| 检测范围 | 0.39–2250 pg/mL |
| 存放说明 | Multi-Component |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |