| 货号 | K151QPD-4 |
| 描述 | Human interleukin-1β (IL-1β), also known as IL-1F2, is a 30.7 kDa pro-inflammatory cytokine that is produced by activated macrophages. IL-1β stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. Along with IL-1α, IL-1β binds directly to IL-1 RI, which is then associated with IL-1 R accessory protein (IL-1RAcP) to form a high-affinity receptor complex for signal transduction. IL-1β is involved in a number of biological activities ranging from aging to wound healing. Along with IFN-γ, IL-6, and TNF-α, IL-1β is a pyrogenic cytokine that induces the production of prostaglandins, the major mediators of fever induction. The Human IL-1β Kit provides the assay-specific components for the quantitative determination of endogenous IL-1β in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Proinflammatory Panel 1 human Calibrator Insert Proinflammatory Panel 1 human Control Insert Proinflammatory Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.04 pg/mL |
| 检测范围 | 0.04–375 pg/mL |
| 存放说明 | Multi-Component |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |