V-PLEX Human CRP Kit CRP | Human
货号：
K151STD-4 基本售价：
询价 规格：
25 plates
产品信息
概述| 货号 | K151STD-4 |
| 描述 | C-reactive protein (CRP) is a 23 kDa, acute phase protein and a critical marker of acute inflammation. It is produced mainly by the liver in response to pro-inflammatory cytokines and lipopolysaccharides (LPS). Upon infection, inflammation, or tissue damage, the level of CRP in human serum can increase >1,000-fold within 6 to 48 hours and return to basal levels (<1 Μg/mL) very quickly, making this protein a key marker for innate host immune responses. In contrast to humans, CRP in mice is expressed at a very low level and is not an acute-phase reactant.9 Human CRP shares 71% and 64% sequence homology with mouse and rat, respectively. CRP has been used as a predictive biomarker for several pathological conditions, including cardiovascular disease, type 2 diabetes, and stroke. CRP binds phosphocholine in the membranes of injured cells as well as nuclear components of necrotic and apoptotic cells that initiate the C1q-complement cascade and immune cell phagocytotic responses for clearance of damaged and apoptotic cells. The Human CRP Kit provides assay-specific components for the quantitative determination of CRP in human serum, plasma, cell culture supernatants, cerebral spinal fluid, and urine. |
| 反应种属 | Human |
| 应用 | Cardiovascular |
性能| 说明书 | Vascular Injury Panel 2 human Insert
|
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 1.33 pg/mL |
| 检测范围 | 1.33–49 608 pg/mL |
| 存放说明 | Multi-Component |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |
