Human TIMP-1 Kit TIMP-1 | Human
货号：
K151JFC-2 基本售价：
询价 规格：
5 plates
产品信息
概述| 货号 | K151JFC-2 |
| 描述 | The Human TIMP-1 Kit provides assay-specific components for the quantitative determination of endogenous tissue inhibitor of metalloproteinase 1 (TIMP-1) in human serum, plasma, and cell supernatant. TIMP-1 is a glycoprotein that regulates the activation and inhibition of the matrix metalloproteinases (MMPs). The N-terminal site of TIMP-1 forms a non-covalent complex with the active site of the MMPs to inhibit active MMP-mediated proteolysis. TIMP-1 is widely present in many tissues and cell types. Overexpression of TIMP-1 correlates with aggressive pathogenesis of a variety of tumors. It has also been shown that total TIMP-1 plasma levels can be related to cardiovascular risk factors influencing cardiovascular remodeling via extracellular matrix degradation. |
| 反应种属 | Human |
| 应用 | Toxicology,Cytokines & Chemokines,Immunology/Inflammation |
性能| 说明书 | Human TIMP-1
|
| 供应商 | MSD |
| 存放说明 | Multi-Component |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |
