V-PLEX NHP IL-12/IL-23p40 Kit IL-12/IL-23p40 | Non-human primate
货号:
K156RJD-2 基本售价:
询价 规格:
5 plates
产品信息
概述货号 | K156RJD-2 |
描述 | Interleukin-12/interleukin 23 p40 (IL-12/IL-23p40)—also known as IL-12B, cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), and NK cell stimulatory factor chain 2 (NKSF2)—is a glycosylated protein with five internal disulfide bonds. This cytokine can form heterodimers by binding to the IL-12A subunit or the IL-23 p19 subunit to form IL-12 and IL-23, respectively. It can also dimerize with itself to form the p80 homodimer. It acts as a growth factor for activated T and NK cells and stimulates NK/lymphokine-activated killer cells and IFN-γ production. IL-12/IL-23 p40 binds to IL-12Rβ1 which is part of both IL-12 and IL-23 receptor complexes. It is involved in Mendelian susceptibility to mycobacterial disease (MSMD) and psoriasis type 11. The NHP IL-12/IL-23p40 Kit provides assay-specific components for the quantitative determination of endogenous IL-12/IL-23p40 in non-human primate urine, serum, plasma, and cell culture supernatants. |
反应种属 | Non-human primate |
应用 | Cytokines & Chemokines,Immunology/Inflammation |
性能说明书 | Cytokine Panel 1 NHP Insert
|
供应商 | MSD |
样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
灵敏度 | 0.39 pg/mL |
检测范围 | 0.39–2250 pg/mL |
存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
产品用途 | For Research Use Only. Not for use in diagnostic procedures. |