| 货号 | K151NRG-2 |
| 描述 | Human MIP-1β (CCL4)—also known as lymphocyte activation gene 1 protein (LAG-1), G-26 T-lymphocyte-secreted protein, HC21, PAT 744, protein H400, SIS-gamma, small-inducible cytokine A4, and T-cell activation protein 2 (ACT-2)—is a 10.2 kDa protein that binds to CCR5. CCR5 is shared between MIP-1β, MIP-1α, RANTES, and CCL3L1. MIP-1β is one of the major HIV suppressive factors produced by CD8+ T cells. It down-modulates the expression of CCR5 and thus inhibits the CCR5-mediated entry of HIV-1 into T-cells. MIP-1β occurs as a homodimer and as a heterodimer with MIP-1α. In addition to its involvement in HIV infection, MIP-1β plays a role in large granular lymphocyte leukemia and organ transplant rejection. The Human MIP-1β Kit provides assay-specific components for the quantitative determination of endogenous MIP-1β in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Chemokine Panel 1 human Calibrator Insert Chemokine Panel 1 human Control Insert Chemokine Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.37 pg/mL |
| 检测范围 | 0.37–750 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |