| 货号 | K151QSG-2 |
| 描述 | Human interleukin-5 (IL-5), also known as B-cell growth factor II (BCGF-II) and T-cell replacing factor (TRF), is a glycosylated 15.2 kDa homodimer protein with two internal disulfide bonds. It is mainly produced by eosinophils and Th2 cells. Its main function is to induce terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. The IL-5 receptor consists of an α subunit and a βc subunit that is shared with the GM-CSF receptor. IL-5 initially binds to the α subunit with low affinity and then associates with the pre-formed βc subunit homodimer yielding a high-affinity interaction. IL-5 is associated with eosinophilia, atopic dermatitis, and pulmonary fibrosis along with other disorders.The Human IL-5 Kit provides assay-specific components for the quantitative determination of endogenous IL-5 in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Cytokine Panel 1 human Calibrator Insert Cytokine Panel 1 human Control Insert Cytokine Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.22 pg/mL |
| 检测范围 | 0.22–562 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |