| 货号 | K151RFG-2 |
| 描述 | Human interleukin-17A (IL-17A), also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA-8), is a glycosylated 17.5 kDa homodimer protein with two disulfide bonds. It induces stromal cells to produce proinflammatory and hematopoietic cytokines, and it enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. IL-17A is a positive regulator of IL-23 production and is a key component of the Th17 pathway. IL-17A can dimerize with IL-17F. The receptor for the IL-17A, IL-17F, and IL-17A/IL-17F hetereodimer consists of IL-17RA and IL-17RC. IL-17A is involved in human rhinovirus infection and Sjogren’s syndrome. The Human IL-17A Kit provides assay-specific components for the quantitative determination of endogenous IL-17A in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Cytokine Panel 1 human Calibrator Insert Cytokine Panel 1 human Control Insert Cytokine Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.74 pg/mL |
| 检测范围 | 0.74–3653 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |