| 货号 | K151QUG-2 |
| 描述 | Human interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is a 20.5 kDa, glycosylated homodimeric cytokine with two disulfide bonds. The homodimer binds to two IL-10 Rα subunits resulting in recruitment of two IL-10 Rβ chains to initiate the IL-10 mediated signal cascades. IL-10 Rβ is also associated with receptors of IL-22, IL-26, IL-28, and IL-29. IL-10 inhibits the synthesis of numerous cytokines (including IFN-γ, IL-2, IL-3, TNF-α, TNF-β, and GM-CSF) that suppress Th1 proinflammatory responses and promote phagocytic uptake. IL-10 has been shown to prevent liver necrosis during parasitic infection in mice.The Human IL-10 Kit provides the assay-specific components for the quantitative determination of endogenous IL-10 in human urine, serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Proinflammatory Panel 1 human Calibrator Insert Proinflammatory Panel 1 human Control Insert Proinflammatory Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | 0.03 pg/mL |
| 检测范围 | 0.03–233 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |