| 货号 | K15047G-2 |
| 描述 | Chemokines are small chemotactic cytokines with molecular weights around 8–10 kDa that are capable of inducing directed chemotaxis. Four cysteine residues in conserved locations result in a compact 3-dimensional structure. Based on the spacing of the first two cysteine residues, chemokines are divided into four families: CC chemokines, CXC chemokines, C chemokines, and CX3C chemokines, where C represents cysteine and X represents any other amino acid. Chemokines function by activating specific G protein-coupled receptors resulting in migration of inflammatory and non-inflammatory cells. The pro-inflammatory chemokines are responsible for migration of immune cells to the infection site, while the homeostatic chemokines are responsible for recruiting cells for tissue maintenance and development. The Chemokine Panel 1 (human) Kit provides assay-specific components for the quantitative determination of eight CC chemokine (eotaxin, MIP-1β, eotaxin-3, TARC, MIP-1α, MCP-1, MDC, MCP-4) and two CXC chemokine assays (IP-10, IL-8). This kit may be used for the analysis of all or any combination of these chemokine biomarkers in cell culture supernatants, serum, plasma, and urine. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | Chemokine Panel 1 human Calibrator Insert Chemokine Panel 1 human Control Insert Chemokine Panel 1 human Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Urine, Cell Culture Supernatant |
| 灵敏度 | Eotaxin: 3.26 pg/mL MIP-1β: 0.37 pg/mL Eotaxin-3: 1.77 pg/mL TARC: 0.22 pg/mL IP-10: 0.37 pg/mL MIP-1α: 3.02 pg/mL IL-8(HA): 95.6 pg/mL MCP-1: 0.09 pg/mL MDC: 1.22 pg/mL MCP-4: 1.69 pg/mL |
| 检测范围 | Eotaxin: 3.26–1120 pg/mL MIP-1β: 0.37–750 pg/mL Eotaxin-3: 1.77–3750 pg/mL TARC: 0.22–1120 pg/mL IP-10: 0.37–500 pg/mL MIP-1α:3.02–743 pg/mL IL-8(HA): 95.6–43 400 pg/mL MCP-1: 0.09–375 pg/mL MDC: 1.22–750 |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |