U-PLEX Chemokine Combo 2 (hu) SECTOR (1PL) CTACK, ENA-78, Fractalkine, I-309, I-TAC, MIF, MIP-3α, MIP-3β, MIP-5, SDF-1α | Human
货号:
K15046K-1 基本售价:
询价 规格:
1 plate
产品信息
概述货号 | K15046K-1 |
描述 | Chemokines are small chemotactic cytokines with molecular weights around 8–10 kDa that are capable of inducing directed chemotaxis. Four cysteine residues in conserved locations result in a compact 3-dimensional structure. Based on the spacing of the first two cysteine residues, chemokines are divided into four families: CC chemokines, CXC chemokines, C chemokines, and CX3C chemokines, where C represents cysteine and X represents any other amino acid. Chemokines function by activating specific G protein-coupled receptors resulting in migration of inflammatory and non-inflammatory cells. The proinflammatory chemokines are responsible for migration of immune cells to the infection site, while the homeostatic chemokines are responsible for recruiting cells for tissue maintenance and development. |
反应种属 | Human |
应用 | Cytokines & Chemokines,Immunology/Inflammation |