| 货号 | K156UQK-2 |
| 描述 | MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Interleukin-12p40/interleukin 23p40 , also known as IL-12B, cytotoxic lymphocyte maturation factor 40 kDa subunit (CLMF p40), and NK cell stimulatory factor chain 2 (NKSF2), is a glycosylated 37.2 kDa protein with five internal disulfide bonds. This cytokine can form heterodimers by binding to the IL-12A subunit or the IL-23p19 subunit to form IL-12 and IL-23, respectively. It can also dimerize with itself to form the p80 homodimer. It acts as a growth factor for activated T and NK cells and stimulates NK/lymphokine-activated killer cells and IFN-γ production. IL-12/IL-23p40 binds to IL-12Rβ1 which is part of both IL-12 and IL-23 receptor complexes. The U-PLEX NHP IL-12/IL-23p40 Assay provides the components for the quantitative determination of both natural and recombinant IL-12/IL-23p40 in Cynomolgus monkey and Rhesus monkey serum, plasma, and cell culture supernatants. |
| 反应种属 | Non-human primate |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | U-PLEX Biomarker Group 1 NHP - Multiplex Assays - Product Insert U-PLEX Biomarker Group 1 NHP - Singleplex Assays - Product Insert U-PLEX NHP Group 1 Custom Product Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Cell Culture Supernatant |
| 灵敏度 | 2.8pg/mL |
| 检测范围 | 2.8-21,000 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |