| 货号 | K151VDK-2 |
| 描述 | MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Cutaneous T-cell attracting chemokine (CTACK/CCL27) is a small chemotactic cytokine belonging to the CC family of chemokines which has well-appreciated roles in adhesion and directional homing of immune and inflammatory cells. It is pivotal in mediating the migration of lymphocytes into the skin by binding to the chemokine receptor CCR10. CTACK is predominantly and continuously expressed in the skin by keratinocytes and is highly upregulated in wounds and in inflammatory diseases like atopic dermatitis and psoriasis. Studies have shown that CTACK-CCR10 interaction directly regulates T-cell recruitment to inflamed skin and is the likely key regulator of basal T-cell trafficking during immunosurveillance. The U-PLEX Human CTACK Assay provides the components for the quantitative determination of both natural and recombinant human cutaneous T cell-attracting chemokine (CTACK) in serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | U-PLEX Biomarker Group 1 Human - Multiplex Assays - Product Insert U-PLEX Biomarker Group 1 Human - Singleplex Assays - Product Insert U-PLEX Custom Group 1 Human - Product Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Cell Culture Supernatant |
| 灵敏度 | 1.8 pg/mL |
| 检测范围 | 1.8-4,200 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |