| 货号 | K151VKK-2 |
| 描述 | MSD offers a range of individual assays utilizing U-PLEX Antibody Sets that provide a rapid and convenient method for measuring biomarkers in complex matrices. The individual assays are offered on MSD GOLD Small Spot Streptavidin Plates and use the same antibody sets and diluents as the U-PLEX multiplex assays. This allows for efficient transfer between the individual assay and a higher throughput multiplex configuration. Typical of assays developed on the MSD platform, the individual assays have high sensitivity, excellent precision, provide up to five-logs of linear dynamic range, and require minimal sample volume. Thrombopoietin (TPO), also known as megakaryocyte growth and development factor (MGDF), is a glycoprotein hormone that is the key regulator of megakaryopoiesis and thrombopoiesis. TPO is constitutively expressed by liver and bone marrow cells and is cleared from circulation by binding to the cMPL receptor. TPO stimulates bone marrow progenitor cells to proliferate and mature into megakaryocytes that produce platelets, which play critical roles in hemostasis. Circulating TPO levels may be useful in differentiating thrombocytopenias caused by peripheral destruction from those due to thrombopoietic failure; in the former, levels are depressed while in the latter levels are elevated. Elevated TPO levels may also serve as a biomarker for vascular damage and coronary angina. TPO may enhance platelet aggregation and platelet/monocyte interactions. The U-PLEX Human TPO Assay provides the components for the quantitative determination of both natural and recombinant human TPO in serum, plasma, and cell culture supernatants. |
| 反应种属 | Human |
| 应用 | Cytokines & Chemokines,Immunology/Inflammation |
| 说明书 | U-PLEX Biomarker Group 1 Human - Multiplex Assays - Product Insert U-PLEX Biomarker Group 1 Human - Singleplex Assays - Product Insert U-PLEX Custom Group 1 Human - Product Insert |
| 供应商 | MSD |
| 样本类型以及上样量 | Serum, Plasma, Cell Culture Supernatant |
| 灵敏度 | 19 pg/mL |
| 检测范围 | 19-40,400 pg/mL |
| 存放说明 | Please refer to the product insert for the storage conditions of individual kit components. |
| 产品用途 | For Research Use Only. Not for use in diagnostic procedures. |