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货号： bs-6518R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-6518R
- 英文名称
- CDK5RAP3
- 中文名称
- 周期素依赖性激酶5激活结合蛋白C53抗体
- 别 名
- C53; CDK5 activator binding protein C53; CDK5 regulatory subunit associated protein 3; HSF 27; HSF27; IC53; Ischemic heart CDK5 activator binding protein C53; LXXLL/leucine zipper containing ARFbinding protein; LZAP; MST016; OK/SW cl.114; PP1553; CK5P3_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞周期蛋白 转录调节因子 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Sheep,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 57kDa
- 细胞定位
- 细胞核 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CDK5RAP3:51-150/506
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.
Function:
CDK5RAP3 may be involved in cell proliferation through regulation of the CDK5 family by interaction with CDK5 receptor 1.
Subunit:
Interacts with CDK5R1. This interaction is prevented by the association between CDK5R1 and CDK5RAP3. Interacts with the enteric adenovirus serotype 41 fiber protein. Interacts with UFL1.
Tissue Specificity:
Ubiquitous. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform 3 is expressed in kidney, liver, skeletal muscle and placenta.
Post-translational modifications:
Phosphorylated in vitro by CDK5
Similarity:
Belongs to the CDK5RAP3 family.
SWISS:
Q96JB5
Gene ID:
80279
Database links:Entrez Gene: 80279 Human
Entrez Gene: 80280 Mouse
Entrez Gene: 80278 Rat
Omim: 608202 Human
SwissProt: Q96JB5 Human
SwissProt: Q99LM2 Mouse
SwissProt: Q9JLH7 Rat
Unigene: 20157 Human
Unigene: 28297 Mouse
Unigene: 3727 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.