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货号： bs-4687R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4687R-AP
- 英文名称
- Anti-AMH/AP
- 中文名称
- 碱性磷酸酶（AP）标记的Muellerian缪勒管激素抑制因子抗体
- 别 名
- MIS_HUMAN; Anti muellerian hormone; MIF; MIS; Muellerian inhibiting factor; Mullerian inhibiting substance; Muellerian-inhibiting factor; Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 发育生物学 信号转导 干细胞 生长因子和激素 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- WB=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 57kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human AMH
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008].
Function:
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Secreted.
DISEASE:
Persistent Muellerian duct syndrome 1 (PMDS1) [MIM:261550]: A form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the TGF-beta family.
Database links:Entrez Gene: 268 Human
Entrez Gene: 11705 Mouse
Entrez Gene: 25378 Rat
Omim: 600957 Human
SwissProt: P03971 Human
SwissProt: P27106 Mouse
SwissProt: P49000 Rat
Unigene: 112432 Human
Unigene: 19121 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.