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货号: bs-7076R-AP 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-7076R-AP
- 英文名称
- Anti-BMP11/AP
- 中文名称
- 碱性磷酸酶(AP)标记的骨形态发生蛋白11抗体
- 别 名
- BMP 11 BMP11; Bone morphogenetic protein 11; GDF 11; Growth differentiation factor 11; GDF11_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 生长因子和激素 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Chicken, Pig, Cow, Rabbit, Sheep,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 12kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BMP11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
BMP11 is a member of the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. BMP11 is a secreted signal that acts globally to specify positional identity along the anterior/ posterior axis during development. It plays critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Function:
Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Secreted (Probable).
Similarity:
Belongs to the TGF-beta family.
Database links:
UniProtKB/Swiss-Prot: O95390.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.