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货号： bs-7853R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7853R-AP
- 英文名称
- Anti-ABCA9/AP
- 中文名称
- 碱性磷酸酶（AP）标记的三磷酸腺苷结合盒转运蛋白9抗体
- 别 名
- ATP binding cassette A9; ATP binding cassette sub family A (ABC1) member 9; ATP binding cassette sub family A member 9; DKFZp686F2450; EST640918; MGC75415; ABCA9_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 细胞周期蛋白 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Horse,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 184kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ABCA9
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ABCA9 is a member of the superfamily of ATP-binding cassette (ABC) transporters and contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA9 is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of the ABCA9 gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. ABCA9 May play a role in monocyte differentiation and lipid homeostasis.
Function:
May play a role in monocyte differentiation and lipidhomeostasis.
Subcellular Location:
Membrane; Multi-pass membrane protein(Potential).
Tissue Specificity:
Widely expressed with higher expression inheart.
Similarity:
Belongs to the ABC transporter superfamily. ABCAfamily.
Contains 2 ABC transporter domains.
Database links:Entrez Gene: 10350 Human
Entrez Gene: 217262 Mouse
Entrez Gene: 287788 Rat
Omim: 612507 Human
SwissProt: Q8IUA7 Human
SwissProt: Q8K449 Mouse
Unigene: 131686 Human
Unigene: 291459 Mouse
Unigene: 98251 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.