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货号： bs-8072R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8072R-AP
- 英文名称
- Anti-AGFG1/AP
- 中文名称
- 碱性磷酸酶（AP）标记的艾滋病病毒复制结合蛋白抗体
- 别 名
- HIV 1 Rev binding protein; RAB; Rev/Rex activation domain-binding protein; RIP; AGFG1; AGFG1_HUMAN; Arf-GAP domain and FG repeats-containing protein 1; ArfGAP with FG repeats 1; HIV-1 Rev-binding protein; HRB; Nucleoporin like protein RIP; Nucleoporin-like protein RIP; Rev interacting protein; Rev-interacting protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 细菌及病毒
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human AGFG1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
Function:
Required for vesicle docking or fusion during acrosomebiogenesis (By similarity). May play a role in RNA trafficking orlocalization. In case of infection by HIV-1, acts as a cofactor forviral Rev and promotes movement of Rev-responsiveelement-containing RNAs from the nuclear periphery to thecytoplasm. This step is essential for HIV-1 replication.
Subunit:
Interacts with EPS15R and EPS15. Interacts with FCHO1.
Subcellular Location:
Nucleus. Cytoplasmic vesicle.
Tissue Specificity:
Ubiquitously expressed.
Post-translational modifications:
O-glycosylated (By similarity).
Similarity:
Contains 1 Arf-GAP domain.
Database links:Entrez Gene: 536149 Cow
Entrez Gene: 3267 Human
Entrez Gene: 15463 Mouse
Entrez Gene: 363266 Rat
Omim: 600862 Human
SwissProt: Q2TA45 Cow
SwissProt: P52594 Human
SwissProt: Q8K2K6 Mouse
SwissProt: Q4KLH5 Rat
Unigene: 352962 Human
Unigene: 392569 Mouse
Unigene: 433409 Mouse
Unigene: 3734 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.