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货号： bs-4911R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4911R-AP
- 英文名称
- Anti-Reg3 beta/AP
- 中文名称
- 碱性磷酸酶（AP）标记的胰岛β细胞生长因子Reg IIIα 抗体
- 别 名
- Pap; Pap1; REG3B_MOUSE; Regenerating islet-derived protein 3-beta; REG-3-beta; Pancreatitis-associated protein 1; Regenerating islet-derived protein III-beta; Reg III-beta.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Mouse, Rat,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from mouse Reg3 beta
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Specifically, increased expression of Reg III Alpha results in pancreatic inflammation and liver carcinogenesis. Reg III Alpha, also de-signated pancreatitis-associated protein, localizes to the apical region of pancreatic acinar cells and is similar to the C-type lectin superfamily. The Reg III Alpha protein is mainly expressed in the intestine, with lower expression detected in healthy pancreas. It is also detected in pancreatic juice as a result of pancreatic inflammation.
Function:
Might be a stress protein involved in the control of bacterial proliferation.
Subcellular Location:
Secreted. Found in the apical region of pancreatic acinar cells.
Tissue Specificity:
Constitutively expressed in the small intestine, moderately in colon and at an extremely low level in healthy pancreas.
DISEASE:
Note=Overexpressed during the acute phase of pancreatitis.
Similarity:
Contains 1 C-type lectin domain.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.