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货号： bs-11200R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11200R-AP
- 英文名称
- Anti-LHX2/AP
- 中文名称
- 碱性磷酸酶（AP）标记的调控胚胎干细胞分化蛋白Lhx2抗体
- 别 名
- hLhx2; Homeobox protein LH-2; Homeobox protein LH2; LH2; LHX2; LHX2_HUMAN; LIM homeobox 2; LIM homeobox protein 2; LIM HOX gene 2; LIM/homeobox protein Lhx2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 干细胞 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LHX2(248-296aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The overlapping expression of LHX1, LHX3, LHX4, Isl-1 and Isl-2 in developing motor neurons along the spinal column may influence the establishment of specific motor neuron subtypes. The human LHX2 gene maps to chromosome 9q33.3 and encodes a 389 amino acid protein. LHX2 is involved in early patterning of the telencephalon, where the neuroepithelium is first divided into cortical tissue and cortical hem.
Function:
Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types.
Subunit:
Contains 1 homeobox DNA-binding domain.Contains 2 LIM zinc-binding domains.
Subcellular Location:
Nucleus.
Similarity:
Contains 1 homeobox DNA-binding domain.
Contains 2 LIM zinc-binding omains.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.