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货号： bs-4649R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4649R-AP
- 英文名称
- Anti-Parvovirus Capsid protein VP1/AP
- 中文名称
- 碱性磷酸酶（AP）标记的大鼠细小病毒H-1株(H-1)抗体
- 别 名
- Parvovirus h-1 coat; CAPSD_PAVHH; Capsid protein VP1; Coat protein VP1; H-1 Parvovirus Capsid protein VP1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 细菌及病毒
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Murine minute virus (H-1 parvovirus)
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 81kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from H-1 parvovirus Capsid protein VP1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and putative nuclear localization signal(s). VP1 N-terminus might serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.
Subcellular Location:
Virion. Host nucleus.
Similarity:
Belongs to the parvoviridae capsid protein family.
Database links:
UniProtKB/Swiss-Prot: P03136
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
大鼠H-1病毒株是由Toolan(1960)从经大鼠传代的人肿瘤细胞系(HEP-1)分离到得第2株大鼠细小病毒(RPV),通常称为H-1病毒,又称Toolan病毒。