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货号： bs-6958R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6958R-AP
- 英文名称
- Anti-ZDHHC-12/AP
- 中文名称
- 碱性磷酸酶（AP）标记的锌指蛋白Zdhhc12抗体
- 别 名
- DHHC12; DHHC-12; Palmitoyltransferase ZDHHC12; ZDH12_HUMAN; Zdhhc12; Zinc finger DHHC domain-containing protein 12;DHHC-12; Probable palmitoyltransferase ZDHHC12; ZDH12_HUMAN; ZDHHC12; Zinc finger DHHC domain-containing protein 12; Zinc finger DHHC type containing 12; Zinc finger protein 400; ZNF400.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 锌指蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZDHHC-12
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC12 (zinc finger, DHHC domain containing 12), also known as ZNF400, is a 267 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to a S-palmitoyl protein and free CoA. Three isoforms exist due to alternative splicing events. The gene encoding ZDHHC12 maps to human chromosome 9, which consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Chromosome 9 is considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype.
Subcellular Location:
Membrane; Multi-pass membrane protein
Similarity:
Belongs to the DHHC palmitoyltransferase family.
Contains 1 DHHC-type zinc finger.
Database links:Entrez Gene: 505354Cow
Entrez Gene: 608478Dog
Entrez Gene: 100066906Horse
Entrez Gene: 84885Human
Entrez Gene: 100519816Pig
Entrez Gene: 366014Rat
SwissProt: Q96GR4Human
SwissProt: Q6DGF5Rat
Unigene: 133122Human
Unigene: 95138Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.