产品中心
当前位置：首页>产品中心Anti-SCGN/AP
货号： bs-11754R-AP 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11754R-AP
- 英文名称
- Anti-SCGN/AP
- 中文名称
- 碱性磷酸酶（AP）标记的钙结合样蛋白/神经内分泌肿瘤标记物抗体
- 别 名
- Calbindin like; CALBL; DJ501N12.8; Scgn; SECRET; Secretagogin; Secretagogin EF hand calcium binding protein; SEGN; SEGN_HUMAN; Setagin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Secretagogin (221-276aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation. [provided by RefSeq, Jul 2008]
Subcellular Location:
Cytoplasm. Secreted.Cytoplasmic vesicle, secretory vesicle membrane; Peripheralmembrane protein; Cytoplasmic side.Note=Predominantly cytoplasmic. A small proportion is associatedwith secretory granules and membrane fractions.Detectable in human serum after ischemic neuronal damage.
Tissue Specificity:
Expressed at high levels in the pancreatic islets of Langerhans and to a much lesser extent in the gastrointestinal tract (stomach, small intestine and colon), the adrenal medulla and cortex and the thyroid C-cells. In the brain, the expression is restricted to distinct subtypes of neurons with highest expression in the molecular layer of the cerebellum (stellate and basket cells), in the anterior part of the pituitary gland, in the thalamus, in the hypothalamus and in a subgroup of neocortical neurons.
Similarity:
Contains 6 EF-hand domains.
Database links:Entrez Gene: 10590Human
Entrez Gene: 306942Rat
Omim: 609202Human
SwissProt: O76038Human
SwissProt: Q6R556Rat
Unigene: 116428Human
Unigene: 53156Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.