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货号： bs-7165R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7165R-RBITC
- 英文名称
- Anti-ZNF141/RBITC
- 中文名称
- 罗丹明（RBITC）标记的锌指蛋白141抗体
- 别 名
- D4S90; PAPA6; pHZ-44; Zinc finger protein 141.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF141
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders.
Function:
May be involved in transcriptional regulation as a repressor. Plays a role in limb development.
Subcellular Location:
Nuclear.
DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.
Disease description:A condition characterized by the occurrence of supernumerary digits in the upper and/or lower extremities. In postaxial polydactyly type A, the extra digit is well-formed and articulates with the fifth or a sixth metacarpal/metatarsal.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.Contains 11 C2H2-type zinc fingers.Contains 1 KRAB domain.
Database links:Entrez Gene: 7700Human
Omim: 194648Human
SwissProt: Q15928Human
Unigene: 654355Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.