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货号： bs-12735R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12735R-RBITC
- 英文名称
- Anti-PLS1/RBITC
- 中文名称
- 罗丹明（RBITC）标记的肠道特异性凝血酶PLS1抗体
- 别 名
- Fimbrin; I Fimbrin; I Plastin; Intestine specific plastin; Plastin 1 (I isoform); Plastin 1; Plastin1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 结合蛋白 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 70kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PLS1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5 UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Feb 2010]
Function:
Actin-bundling protein in the absence of calcium.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
In small intestine, colon, and kidney; relatively lower levels of expression are detected in the lung and stomach.
Post-translational modifications:
Phosphorylated.
Similarity:
Contains 2 actin-binding domains.
Contains 4 CH (calponin-homology) domains.
Contains 2 EF-hand domains.
Database links:Entrez Gene: 5357Human
Entrez Gene: 102502Mouse
Entrez Gene: 315926Rat
Omim: 602734Human
SwissProt: Q14651Human
SwissProt: Q3V0K9Mouse
Unigene: 203637Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.