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货号： bs-21031R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21031R-RBITC
- 英文名称
- Anti-SLD5/RBITC
- 中文名称
- 罗丹明（RBITC）标记的SLD5蛋白抗体
- 别 名
- DNA replication complex GINS protein SLD5; GINS complex subunit 4 (Sld5 homolog); GINS complex subunit 4; GINS4; SLD5; SLD5 homolog; SLD5 S cerevisiae homolog of; SLD5_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLD5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The yeast heterotetrameric GINS complex is made up of Sld5, Psf1 (GINS1; MIM 610608), Psf2 (GINS2; MIM 610609), and Psf3 (GINS3; MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]). See GINS1 for additional information about the GINS complex.[supplied by OMIM, Mar 2008]
Function:
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS4 is important for GINS complex assembly. GINS complex seems to bind preferentially to single-stranded DNA.
Subcellular Location:
Cytoplasm. Nucleus.
Similarity:
Belongs to the GINS4/SLD5 family.
Database links:Entrez Gene: 770899Chicken
Entrez Gene: 482843Dog
Entrez Gene: 100055757Horse
Entrez Gene: 84296Human
Entrez Gene: 109145Mouse
Entrez Gene: 100738105Pig
Entrez Gene: 290842Rat
Entrez Gene: 703350 Rhesus monkey
Entrez Gene: 572562Zebrafish
Omim: 610611Human
SwissProt: Q9BRT9Human
SwissProt: Q99LZ3Mouse
SwissProt: Q499W2Rat
Unigene: 656996Human
Unigene: 27945Mouse
Unigene: 103411Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.