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货号: bs-19812R-RBITC 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-19812R-RBITC
- 英文名称
- Anti-SLC34A1/RBITC
- 中文名称
- 罗丹明(RBITC)标记的溶质载体家族蛋白34成员A1抗体
- 别 名
- FRTS2; Na(+)-dependent phosphate cotransporter 2A; Na(+)/Pi cotransporter 2A; Na+-phosphate cotransporter type II; naPi-2a; NAPI-3; naPi2a; NAPI3; NPHLOP1; NPT2; NPTIIa; renal sodium-dependent phosphate transporter; renal sodium/phosphate transporter protein 2; SLC11; SLC17A2; SLC17A2, formerly; NPT2A_HUMAN; sodium-dependent phosphate transport protein 2A; sodium-phosphate transport protein 2A; sodium/phosphate co-transporter; sodium/phosphate cotransporter 2A; sodium/phosphate transporter 2, kidney; solute carrier family 17 (sodium phosphate), member 2; solute carrier family 17, member 2, formerly; solute carrier family 34 (sodium phosphate), member 1; solute carrier family 34 (type II sodium/phosphate.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Rabbit, Sheep, Cat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 69kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC34A1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the type II sodium-phosphate cotransporter family. Mutations in this gene are associated with hypophosphatemia nephrolithiasis/osteoporosis 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Function:
May be involved in actively transporting phosphate into cells via Na+ cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx.
Subunit:
Interacts via its C-terminal region with PDZK2 (By similarity). Interacts with SLC9A3R1.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Kidney and lung.
DISEASE:
The disease is caused by mutations affecting the gene represented in this entry.Disease description:A disease characterized by decreased renal phosphate absorption, renal phosphate wasting, hypophosphatemia, hyperphosphaturia, hypercalciuria, nephrolithiasis and osteoporosis.
Similarity:
Belongs to the SLC34A transporter family.
Database links:Entrez Gene: 282483Cow
Entrez Gene: 100735387 Guinea pig
Entrez Gene: 100058397Horse
Entrez Gene: 6569Human
Entrez Gene: 20505Mouse
Entrez Gene: 100155735Pig
Entrez Gene: 733703Pig
Entrez Gene: 100009392Rabbit
Entrez Gene: 25548Rat
Entrez Gene: 443505Sheep
Omim: 182309Human
SwissProt: Q06495Human
SwissProt: Q60825Mouse
SwissProt: Q28620Rabbit
SwissProt: Q06496Rat
SwissProt: O97704Sheep
Unigene: 936Human
Unigene: 276355Mouse
Unigene: 92022Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.