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货号： bs-2088R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-2088R-RBITC
- 英文名称
- Anti-Rabies virus Glycoprotein/RBITC
- 中文名称
- 罗丹明（RBITC）标记的狂犬病病毒糖蛋白抗体
- 别 名
- Rabies virus G; RV Glycoprotein; Rabies virus.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细菌及病毒
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Rabies virus
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from Rabies virus Glycoprotein
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Subunit:
Homotrimer. Interacts with matrix protein.
Subcellular Location:
Virion membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Post-translational modifications:
Glycosylated and palmitoylated by host. Glycosylation is crucial for glycoprotein export at the cell surface. {ECO:0000269|PubMed:1587845, ECO:0000269|PubMed:9451021}.
Similarity:
Belongs to the lyssavirus glycoprotein family.
Database links:Entrez Gene: 1489856Rabies virus
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.