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货号： bs-19494R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19494R-RBITC
- 英文名称
- Anti-NT5M/RBITC
- 中文名称
- 罗丹明（RBITC）标记的线粒体NT5M抗体
- 别 名
- 3-nucleotidase; 5; 5(3)-deoxyribonucleotidase; 5(3)-deoxyribonucleotidase, mitochondrial; 5,3-nucleotidase, mitochondrial; Deoxy-5-nucleotidase 2; dNT-2; DNT2; mitochondrial; NT5M; NT5M_HUMAN,
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NT5M
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a 5 nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5- and 2(3)-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]
Function:
Dephosphorylates specifically the 5 and 2(3)-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP.
Subcellular Location:
Mitochondrion.
Tissue Specificity:
Highly expressed in heart, brain and skeletal muscle. Detected at very low levels in kidney and pancreas.
Similarity:
Belongs to the 5(3)-deoxyribonucleotidase family.
Database links:Entrez Gene: 56953Human
SwissProt: Q9NPB1Human
Unigene: 513977Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.