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货号: bs-19509R-RBITC 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-19509R-RBITC
- 英文名称
- Anti-NUDT12/RBITC
- 中文名称
- 罗丹明(RBITC)标记的NUDT12蛋白抗体
- 别 名
- 0610016O18Rik; DKFZP761I172; EC 3.6.1.22; Nucleoside diphosphate linked moiety X motif 12; Nucleoside diphosphate linked moiety X type motif 12; Nudix (nucleoside diphosphate linked moiety X) type motif 12; Nudix motif 12; Nudix type motif 12; NUDT 12; Peroxisomal NADH pyrophosphatase NUDT12.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NUDT12
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors. Nudix hydrolases, such as NUDT12, regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances (Abdelraheim et al., 2003 [PubMed 12790796]).[supplied by OMIM, Mar 2008]
Function:
Nucleotides are involved in numerous biochemical reactions and pathways within the cell as substrates, cofactors, and effectors. Nudix hydrolases, such as NUDT12 (Nudix (nucleoside diphosphate linked moiety X)-type motif 12), regulate the concentrations of individual nucleotides and of nucleotide ratios in response to changing circumstances. NUDT12 hydrolyzes NAD(P)H to NMNH and AMP (2,5-ADP), and diadenosine diphosphate to AMP. It also has moderate activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. It may regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism.
Subcellular Location:
Peroxisome
Database links:Entrez Gene: 83594Human
Omim: 609232Human
SwissProt: Q9BQG2Human
Unigene: 434289Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.