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货号： bs-19556R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19556R-RBITC
- 英文名称
- Anti-NXT1/RBITC
- 中文名称
- 罗丹明（RBITC）标记的核运输因子1抗体
- 别 名
- MTR2; MTR2, yeast, homolog of; NTF2 like export factor 1; NTF2 related export protein 1; NTF2-related export protein 1; NUTF like export factor 1; NXT1; NXT1_HUMAN; P15; Protein P15.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 染色质和核信号 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 16kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NXT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5.
Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.
Similarity:
Contains 1 NTF2 domain.
Database links:Entrez Gene: 29107Human
Entrez Gene: 520351Cow
Entrez Gene: 56488Mouse
Entrez Gene: 296219Rat
Omim: 605811Human
SwissProt: Q2KIW0Cow
SwissProt: Q9UKK6Human
SwissProt: Q9QZV9Mouse
Unigene: 516933Human
Unigene: 34663Mouse
Unigene: 8541Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.