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货号： bs-8623R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8623R-RBITC
- 英文名称
- Anti-TESPA1/RBITC
- 中文名称
- 罗丹明（RBITC）标记的胸腺TESPA1蛋白抗体
- 别 名
- HSPC257;5830405N20Rik; TESP1_HUMAN; KIAA0748; Protein TESPA1; TESPA1 – thymocyte expressed, positive selection associated 1; TESPA1; thymocyte expressed, positive selection associated 1; Uncharacterized protein KIAA0748.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 59kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TESPA1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ release and mitochondrial Ca2+ uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.
Subunit:
Interacts with PLCG1 and GRB2; the association is increased with prolonged stimulation of the TCR and may facilitate the assembly of the LAT signalosome. Interacts with ITPR1. Also interacts with ITPR3 (By similarity). Interacts with HSPA9.
Subcellular Location:
Cytoplasm. Endoplasmic reticulum membrane.
Post-translational modifications:
May be phosphorylated in response to store-operated Ca(+2) entry.
Database links:Entrez Gene: 9840Human
SwissProt: A2RU30Human
Unigene: 33187Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.