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货号： bs-20230R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-20230R-RBITC
- 英文名称
- Anti-PGAM1/RBITC
- 中文名称
- 罗丹明（RBITC）标记的磷酸变位酶1抗体
- 别 名
- BPG dependent PGAM 1; BPG dependent PGAM1; BPG-dependent PGAM 1; OTTHUMP00000059414; PGAM 1; PGAM A; PGAM B; PGAM-B; PGAM1_HUMAN; PGAMA; PGAMB; Phosphoglycerate mutase 1; Phosphoglycerate mutase 1 brain; Phosphoglycerate mutase A; Phosphoglycerate mutase A nonmuscle form; Phosphoglycerate mutase isozyme B.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 29kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PGAM1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
Subunit:
Homodimer.
Tissue Specificity:
In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
Post-translational modifications:
Acetylated at Lys-253, Lys-253 and Lys-254 under high glucose condition. Acetylation increases catalytic activity. Under glucose restriction SIRT1 levels dramatically increase and it deacetylates the enzyme.
Similarity:
Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
Database links:UniProtKB/Swiss-Prot: P18669.2
Entrez Gene: 5223 Human
Entrez Gene: 18648 Mouse
Entrez Gene: 24642 Rat
Omim: 172250 Human
SwissProt: P18669 Human
SwissProt: Q9DBJ1 Mouse
SwissProt: P25113 Rat
Unigene: 592599 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.