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货号： bs-19073R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19073R-RBITC
- 英文名称
- Anti-NDUFA6/RBITC
- 中文名称
- 罗丹明（RBITC）标记的NADH氧化还原酶辅酶6抗体
- 别 名
- LYRM6;NADHB14;Complex I-B14;CI-B14;LYR motif-containing protein 6;NADH-ubiquinone oxidoreductase B14 subunit.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Sheep, Chimpanzee, Rhesus monkey, Gorilla
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 18kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NDUFA6
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
NDUFA6 is a 128 amino acid protein that localizes to the matrix side of the mitochondrial membrane and belongs to the complex I LYR family. Existing as a subunit of the multi-protein membrane respiratory chain NADH dehydrogenase complex (Complex I), NDUFA6 functions as an accessory protein that facilitates the transfer of electrons from NADH to the respiratory chain. The gene encoding NDUFA6 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subunit:
Mammalian complex I is composed of 45 different subunits.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the complex I LYR family.
Database links:Entrez Gene: 458981Chimpanzee
Entrez Gene: 327670Cow
Entrez Gene: 101135077Gorilla
Entrez Gene: 4700Human
Entrez Gene: 67130Mouse
Omim: 602138Human
SwissProt: Q0MQA5Chimpanzee
SwissProt: Q02366Cow
SwissProt: Q0MQA4Gorilla
SwissProt: P56556Human
SwissProt: Q9CQZ5Mouse
Unigene: 274416Human
Unigene: 27570Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.