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货号： bs-10782R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10782R-RBITC
- 英文名称
- Anti-NUP88/RBITC
- 中文名称
- 罗丹明（RBITC）标记的核孔复合体蛋白88抗体
- 别 名
- karyoporin; Nuclear pore complex protein 88; Nuclear pore complex protein88; Nucleoporin 88; Nucleoporin 88 kDa; Nucleoporin 88kDa; Nucleoporin88; Nucleoporin88kDa; Nup 84; NUP 88; Nup84; Prei 2; Prei2; Preimplantation protein 2; Preimplantation protein2; NUP88_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 染色质和核信号 信号转导 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 85kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NUP88
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
NUP88 is a nucleoporin that is an essential component of the nuclear pore complex. It interacts with NUP214/CAN, and is phosphorylated following DNA damage, possibly via the ATM/ATR pathway. NUP88 is also a tumour marker as it is overexpressed in a large number of malignant neoplasms and precancerous dysplasias.
Function:
Essential component of nuclear pore complex.
Subunit:
Interacts with NUP214/CAN.
Subcellular Location:
Nucleus, nuclear pore complex.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Database links:Entrez Gene: 4927 Human
Entrez Gene: 19069 Mouse
Entrez Gene: 113929 Rat
Omim: 602552 Human
SwissProt: Q99567 Human
SwissProt: Q8CEC0 Mouse
SwissProt: O08658 Rat
Unigene: 584784 Human
Unigene: 288962 Mouse
Unigene: 11042 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.