产品中心
当前位置：首页>产品中心Anti-MGAT5B/RBITC
货号： bs-18910R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18910R-RBITC
- 英文名称
- Anti-MGAT5B/RBITC
- 中文名称
- 罗丹明（RBITC）标记的MGAT5B蛋白抗体
- 别 名
- 6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; 6-N-acetylglucosaminyltransferase B; Alpha-1; Alpha-mannoside beta-1; GlcNAc-T Vb; GNT-IX; GNT-Vb; hGnTVb; Mannoside acetylglucosaminyltransferase 5B; Mgat5b; MGT5B_HUMAN; N-acetylglucosaminyl-transferase Vb; N-acetylglucosaminyltransferase IX.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 90kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MGAT5B
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]
Function:
Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Predominantly expressed in brain. Expressed in all area of the adult and fetal brain Also expressed at much lower level in testis, spleen and thymus.
Similarity:
Belongs to the glycosyltransferase 18 family.
Database links:Entrez Gene: 146664Human
Entrez Gene: 268510Mouse
Entrez Gene: 303693Rat
NCBI: NP_001100538.1Rat
Omim: 612441Human
SwissProt: Q3V5L5Human
SwissProt: Q765H6Mouse
Unigene: 144531Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.