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货号: bs-18852R-RBITC 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-18852R-RBITC
- 英文名称
- Anti-METTL7A/RBITC
- 中文名称
- 罗丹明(RBITC)标记的甲基化样蛋白7A抗体
- 别 名
- AAM B; AAMB; DKFZP586A0522; MET7A_HUMAN; Methyltransferase like 7A; Methyltransferase-like protein 7A; METTL 7A; METTL7A; METTL7A methlytransferase like 7A; Protein AAM-B; Protein AAMB.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human METTL7A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
METTL7A is a 244 amino acid protein that is thought to function as a methyltransferase and is encoded by a gene which maps to chromosome 12. Encoding over 1,100 genes, chromosome 12 comprises nearly 4.5% of the human genome and is associated with a number of skeletal deformaties, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to both a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and a natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Additionally, Trisomy 12p (three copies of the p arm of chromosome 12) leads to facial developmental defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism.
Function:
Probable methyltransferase.
Subcellular Location:
Lipid droplet. Endoplasmic reticulum. Membrane.
Similarity:
Belongs to the methyltransferase superfamily.
Database links:Entrez Gene: 25840Human
Entrez Gene: 70152Mouse
SwissProt: Q9H8H3Human
Unigene: 725674Human
Unigene: 728181Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.