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货号： bs-18812R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18812R-RBITC
- 英文名称
- Anti-METTL17/METT11D1/RBITC
- 中文名称
- 罗丹明（RBITC）标记的甲基样蛋白17抗体
- 别 名
- False p73 target gene protein; FLJ20859; Methyltransferase 11 domain containing 1; Methyltransferase 11 domain containing protein 1; Methyltransferase like protein 17 mitochondrial; METTL17; Protein RSM22 homolog mitochondrial.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human METTL17/METT11D1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
- 产品介绍
- background:
METTL17 is a 456 amino acid mitochondrial protein that belongs to the Rsm22 family and methyltransferase superfamily. Existing as three alternatively spliced isoforms, METT11D1 is thought to function as a component of the mitochondrial small ribosomal subunit. The gene encoding METT11D1 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimers disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
Function:
May be a component of the mitochondrial small ribosomal subunit.
Similarity:
Belongs to the methyltransferase superfamily. Rsm22 family.
Database links:Entrez Gene: 64745Human
Entrez Gene: 52535Mouse
Entrez Gene: 305845Rat
SwissProt: Q9H7H0Human
SwissProt: Q3U2U7Mouse
Unigene: 512693Human
Unigene: 5750Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.