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货号： bs-18510R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18510R-RBITC
- 英文名称
- Anti-ZNF366/RBITC
- 中文名称
- 罗丹明（RBITC）标记的锌指蛋白366抗体
- 别 名
- DC-SCRIPT; DCSCRIPT; Dendritic cell specific transcript; FLJ39796; MGC99415; Zfp366; Zfp366 zinc finger protein 366; Zinc finger protein 366; ZN366_HUMAN; ZNF366.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 85kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF366
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ZNF366 is a 744 amino acid nuclear protein that contains eleven C2H2-type zinc fingers and is thought to function in transcriptional regulation. The gene encoding ZNF366 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
Function:
Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.
Subunit:
Interacts with ESR1, NRIP1 and CTBP1.
Subcellular Location:
Nucleus.
Similarity:
Contains 11 C2H2-type zinc fingers.
Database links:Entrez Gene: 167465Human
Entrez Gene: 238803Mouse
Entrez Gene: 100360041Rat
Omim: 610159Human
SwissProt: Q8N895Human
Unigene: 370303Human
Unigene: 343207Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.