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货号： bs-18368R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18368R-RBITC
- 英文名称
- Anti-LRRC17/RBITC
- 中文名称
- 罗丹明（RBITC）标记的富含亮氨酸重复蛋白17抗体
- 别 名
- 37 kDa leucine rich repeat (LRR) protein; 37kDa; 4833425M04Rik; 6130400C22Rik; Leucine-rich repeat-containing protein 17; LRC17_HUMAN; LRRC17; p37NB; UNQ3076/PRO9909.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 50kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LRRC17
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
LRRC17 is a 441 amino acid protein that localizes to the cytoplasm and contains six LRR repeats. The protein is expressed at high levels in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung. LRRC17 is expressed at higher levels in non-neuronal (S-type) neuroblastoma cells than in neuroblastic (N-type) neuroblastoma cells.
Function:
Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors.
Subcellular Location:
Secreted; extracellular space.
Tissue Specificity:
Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells.
Similarity:
Contains 6 LRR (leucine-rich) repeats.
Contains 2 LRRCT domains.
Contains 1 LRRNT domain.
Database links:Entrez Gene: 10234Human
Entrez Gene: 777690Cow
Entrez Gene: 100050177Horse
Entrez Gene: 74511Mouse
Entrez Gene: 100737774Pig
Entrez Gene: 100340395Rabbit
Entrez Gene: 502715Rat
SwissProt: Q8N6Y2Human
SwissProt: Q9CXD9Mouse
Unigene: 567412Human
Unigene: 439963Mouse
Unigene: 207235Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.