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货号： bs-18082R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-18082R-RBITC
- 英文名称
- Anti-HSPA4L/RBITC
- 中文名称
- 罗丹明（RBITC）标记的热休克蛋白70蛋白4样蛋白抗体
- 别 名
- 94kDa; AI461691; APG 1; HS74L_HUMAN; Heat shock 70kDa protein 4 like; MGC117843; MGC187594; Osmotic stress protein 94; Osp94; OTTMUSP00000027739.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 94kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HSPA4L
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, which include the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The HSP 110 family (also known as the HSP 105 family) is composed of HSP 105, Apg-1 and Apg-2. Apg-1, also known as HSPA4L (heat shock 70 kDa protein 4-like) or Osp94 (osmotic stress protein 94), is an 839 amino acid protein that possesses chaperone activity in vitro, where it inhibits aggregation of citrate synthase. A homodimer, Apg-1 subcellularly localizes to cytoplasm and nucleus, and may translocate to nucleus after heat shock.
Function:
The HSPA4L gene, also known as Apg1 or Osp94, belongs to the HSP110 heat shock gene family, which includes three genes encoding highly conserved proteins. HSPA4L is expressed ubiquitously and predominantly in the testis.
Subunit:
Homodimer (By similarity).
Subcellular Location:
Cytoplasm; Nucleus. Note= May translocate to the nucleus after heat shock
Similarity:
Belongs to the heat shock protein 70 family.
Database links:Entrez Gene: 22824Human
Entrez Gene: 18415Mouse
Entrez Gene: 294993Rat
SwissProt: O95757Human
SwissProt: P48722Mouse
SwissProt: P83581Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.