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货号： bs-17852R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17852R-RBITC
- 英文名称
- Anti-MSH5/RBITC
- 中文名称
- 罗丹明（RBITC）标记的MSH5蛋白抗体
- 别 名
- DKFZp434C1615; G7; hMSH5; MGC2939; MSH 5; MSH5; MSH5_HUMAN; mutS (E. coli) homolog 5; mutS homolog 5; mutS homolog 5 (E. coli); MutS protein homolog 5; MutSH5; NG23; OTTHUMP00000029187; OTTHUMP00000029188.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, Xenopus laevis,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 93kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MSH5
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]
Function:
Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis.
Subunit:
Heterooligomer of MSH4 and MSH5. Interacts with HJURP.
Tissue Specificity:
Ubiquitous, but highly expressed in testis, and thymus.
Similarity:
Belongs to the DNA mismatch repair mutS family.
Database links:Entrez Gene: 100139295Cow
Entrez Gene: 474848Dog
Entrez Gene: 100050672Horse
Entrez Gene: 4439Human
Entrez Gene: 715494Monkey
Entrez Gene: 17687Mouse
Entrez Gene: 100270818Pig
Entrez Gene: 294252Rat
Omim: 603382Human
SwissProt: O43196Human
SwissProt: Q9QUM7Mouse
SwissProt: Q6MG62Rat
Unigene: 647011Human
Unigene: 24192Mouse
Unigene: 44043Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.