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货号： bs-17835R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17835R-RBITC
- 英文名称
- Anti-MRRF/RBITC
- 中文名称
- 罗丹明（RBITC）标记的核糖体再循环因子MRRF抗体
- 别 名
- 2400002D02Rik; MGC93722; mitochondrial; mitochondrial ribosome recycling factor; MRFF; Mrrf; MTRRF; OTTHUMP00000022037; OTTMUSP00000013027; Ribosome recycling factor, mitochondrial; Ribosome recycling factor, mitochondrial precursor; Ribosome-recycling factor; Ribosome-releasing factor; Ribosome-releasing factor, mitochondrial; RP23-324A16.1; RRF; RRFM_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MRRF
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The termination of protein synthesis is carried out by a variety of auxiliary factors that ensure the proper release of newly formed proteins. Once translation is complete, mRNA and P-site deacylated tRNA remain attached to the ribosome in a post-termination complex (post-TC) that must be dissociated and recycled in order for another round of translation to take place. MRRF (mitochondrial ribosome recycling factor), also known as RRF, MRFF or MTRRF, is a 262 amino acid protein that belongs to the RRF (ribosome recycling factor) family. Localized to mitochondria, MRRF is required for the release of ribosomes from mRNA at the end of protein biosynthesis. Via its ability to recycle ribosomes throughout translation, MRRF may actually increase overall translational efficiency, thereby playing an important role in the rate of protein synthesis. Multiple isoforms of MRRF are expressed due to alternative splicing events.
Function:
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the RRF family.
Database links:Entrez Gene: 92399Human
Entrez Gene: 67871Mouse
Entrez Gene: 311903Rat
Omim: 604602Human
SwissProt: Q96E11Human
SwissProt: Q9D6S7Mouse
SwissProt: Q5RKI9Rat
Unigene: 368011Human
Unigene: 378232Mouse
Unigene: 105234Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.